Ateneo - UPO

The course aims to provide the cellular knowledge underlying the correct functioning of immune responses and the main mechanisms responsible for the alteration of the immune system in diseases.

Del Gobbo, Immunologia e Immunopatologia, Piccin

The course aims to provide the basic principles that regulate the immune system. It basically consists of two parts: one that describes basic immunology and therefore allows the student to learn which are the cells and organs of the immune system, as well as the basic processes of pathogen recognition; a second part of immunopathology in which the main diseases originating from defects of the immune system are described.

The student must have the knowledge of the structure of the eukaryotic cell as well as some basic processes of cell biology such as DNA duplication, the splicing process, synthesis and degradation of proteins.

Presentations in MS-Power Point format. Video projector and computer with internet connection and videoconference provided in the classroom. The slides of the lectures will be made available on the teacher's DIR website.

The exam consists of a written test with multiple choice questions, covering the entire program.

The immune system: innate and acquired immunity; cellular and humoral components; primary and secondary lymphatic organs.
B lymphocytes and immunoglobulins: structure, gene recombination, isotypic switch.
T lymphocytes and their receptor: gene structure and recombination; maturation and thymic selection.
The major histocompatibility complex: antigen processing and presentation.
Immunopathology: type I, II, III and IV hypersensitivity; autoimmune diseases; immunodeficiencies; the rejection of transplants.

The necessary tools will be provided to allow students to independently analyze and judge literature data. The student will also improve their skills in the assessment of teaching. •
Communication skills: The student will be able to explain to non-expert people the notions learned, giving and summarizing in a complete but concise way the results achieved using the technical language correctly. The student will be encouraged to familiarize himself with the terms of the discipline, and to transmit the principles, contents and application possibilities with correctness and simplicity to non-experts.