Ateneo - UPO

The course offers an in-depth analysis of the molecular mechanisms underlying molecular target therapies.

Molecular Biology of the cell. Alberts B. ed. Zanichelli.
Papers published on peer reviewed journals provided by the teacher.

The course aims to provide the student with the knowledge of the molecular mechanisms of action of targeted therapies.

Basic knowledge of cellular and molecular biology

Theoretical lectures and exercises with ppt presentation by students and searching of scientific articles in pubmed. In case of the COVID-19 emergency, the lessons will be held at a distance using e-learning technologies, according to the schedule and modality indicated by the administration.

see teaching overview shee

Receptors with intrinsic enzymatic activity, receptors coupled with cytosolic proteins, G coupled receptors, nuclear receptors, enzymes. Targeted cancer therapies: action on cell proliferation, angiogenesis, senescence and apoptosis. Mechanisms of DNA repair. Selection of patients who can benefit from molecular target therapies. Precision medicine.

At the end of the course, the student will have to demonstrate knowledge of the signal transduction pathways generated by the drug interaction / and its target.