Ateneo - UPO

- Guided tissue regeneration: scaffolds, growth factors, active molecules.
- Static and dynamic culture of cells in monolayer and in 3D.
- Techniques for studying tissue regeneration and experimental examples

Principles of Tissue Engineering, Fourth Edition. Edited by: Robert Lanza, Robert Langer and Joseph Vacanti. Academic Press
Slides, scientific publications and laboratory protocols on DIR

Instruct students on concepts such as tissue engineering and tissue regeneration as new therapeutic approaches to help healing and regeneration of damaged biological tissues or to replace them in the case of extensive damage. In addition to theoretical and scientific concepts will be given to students indication about how in vitro is possible to study a new idea together with why is important literature critical analysis. Information will be provided on in vitro study techniques for the development of new devices and for the study of the existing ones.

Knowledge acquired during Bachelor's degree

Lectures with support of videos. Based on Lab availability and on student demand will be possible to attend 4 hours of Lab.

Students with physical disabilities, Learning Disabilities or Special Education Needs can request specific services and tools via the Staff Sviluppo e Coordinamento Carriere e Servizi alle Studentesse e agli Studenti, consulting the University webpage: https://www.uniupo.it/en/services/services-students-physical-or-learning-disabilities

Students with disabilities, learning disabilities or special education needs, once they have contacted the University Staff, can refer to the tutor in charge of the course to define the examination modalities, concerning academic aspects.

Student athlete have the possibility of agreeing with the lecturer on a different exam date in the same session

Three-member examination committee (Professors Bosetti, Borroni and Meneghini). Oral presentation with critical discussion of a scientific paper.

1) Guided tissue regeneration: scaffolds, growth factors, active molecules.
2) Cell culture techniques in monolayer and 3D on scaffolds: how cellular behaviours is modified and which different analysis techniques has to be used (stereomicroscopy, SEM confocal optical fluorescence microscopy; biochemical and molecular techniques, citotoxicity, cell migration, adhesion and proliferation on scaffolds)
3) Techniques for studying tissue regeneration (macroscopic, mechanical, microscopic, biochemical, molecular) and experimental examples with seminars on laboratory experiences in bone and cartilage regeneration

Basics of tissue engineering and tissue regeneration such as therapeutic approaches for healing, regeneration and replacement of damaged biological tissues. Information on in vitro study techniques and the ability to choose the most suitable techniques for the study of a new preparation. Critical analysis of literature from both a theoretical and technical point of view. Thanks to design ideas proposed during the seminars and followed in their development until the clinical study, the student should have learned curiosity and interest in the proposed scientific field with the ability to discuss with the classroom and the teacher about limits and strengths of a scientific paper examined.