Course Details

INTEGRATED DIAGNOSTIC: LABORATORY MEDICINE

MS0965

Course
INTEGRATED DIAGNOSTIC: LABORATORY MEDICINE
Code
MS0965
Academic Year
2025/2026
Curriculum Year
2023/2024
Degree Programme
MEDICINE AND SURGERY
Curriculum
000 - CORSO GENERICO
Course coordinator
Credits
5
Lecture Hours
48
Scientific Disciplinary Sector (SSD)
MED/05 - Clinical Pathology, MED/07 - Microbiology and Clinical Microbiology, BIO/12 - Clinical Biochemistry and Biology
Course Type
Integrated learning activity
Course Delivery
OBB - Obbligatoria
Year
3
Teaching period
Secondo Semestre
Campus
ALESSANDRIA
Teaching language
Italian
Course Contents
CLINICAL PATHOLOGY
Generation and interpretazion of data in laboratory medicine. Hematology. Hemostasis. Kidney function. Immunometry.

CLINICAL MICROBIOLOGY
This course is aimed at understanding the basic principles of the microbiological diagnostics to approach properly the diagnosis of infectious diseases. Using the knowledge acquired in the Medical Microbiology course, the students must know how to manage the diagnosis of infectious diseases. Specifically, they must know: i) which biological sample must be harvested and used for the microbiological diagnosis; ii) which infectious agent may be the cause of the current infection; iii) how to formulate the request to the clinical microbiology laboratory: and iv) how to interpret the results and their clinical significance. A brief description of the main microbiological techniques is also provided.
Reference Texts
CLINICAL PATHOLOGY
La Posata, Medicina di Laboratorio

CLINICAL MICROBIOLOGY
Patrick R. Murray, Ken S. Rosenthal. “Microbiologia Medica” 7a edizione
-Kenneth J. Ryan, C. George Ray. “Sherris. Medical Microbiology” 6th edition
- Guido Antonelli Principi di Microbiologia Medica (II Edizione) Casa Editrice Ambrosiana
Learning Outcomes
CLINICAL PATHOLOGY
To provide a thorough knowledge of Laboratory Medicine, a science that
studies the alterations of the organism in the disease state, using
chemical, physical, genetici and biological methods, obtaining, from
patient biological samples, qualitative and quantitative data, which
provide indispensable information for the clinician, not only for diagnostic
purposes, but also for therapeutic, preventive, prognostic and
rehabilitation purposes. Students will acquire autonomous judgement, ability to communicate using adequate terminology, and capacity of continuous updating

CLINICAL MICROBIOLOGY
How to manage the diagnosis of infectious diseases. How to recognize from the clinical symptoms the type of infectious agent that may be involved. Which biological sample must be harvested with the right timing. How to interpret the results of the microbiological analysis and provide the clinical significance.
Prerequisites
CLINICAL PATHOLOGY
Good knowledge of Chemistry, Biochemistry, Immunology, Molecular Biology and
Genetics.

CLINICAL MICROBIOLOGY
The students must have the knowledge acquired during the basic course of Medical Microbiology
Teaching Methods
CLINICAL PATHOLOGY
Frontal teaching with slides. The slides are available, including slides with vocal comment. Interactivity is promoted by discussion of scientific articles and optional attendance at the analysis laboratory

CLINICAL MICROBIOLOGY
The teaching activity is supported by slide presentation. All the teaching material will be available through the DIR website and must be used to prepare the exam along with the indicated textbooks.
Additional Information
CLINICAL PATHOLOGY
Laboratory exercises at Clinical Chemistry Unit, "Maggiore della Carità"
Hospital, Novara, during which will be deepened the topics, previously
discussed during the lessons

CLINICAL MICROBIOLOGY
Students with physical disabilities, Learning Disabilities or Special Education Needs can request specific services and tools via the Staff Sviluppo e Coordinamento Carriere e Servizi alle Studentesse e agli Studenti, consulting the University webpage: https://www.uniupo.it/en/services/services-students-physical-or-learning-disabilities

Students with disabilities, learning disabilities or special education needs, once they have contacted the University Staff, can refer to the tutor in charge of the course to define the examination modalities, concerning academic aspects
Assessment Methods
CLINICAL PATHOLOGY
written test (multiple choice questions). The examination assesses knowledge of the main principles and technical terminology of laboratory medicine

CLINICAL MICROBIOLOGY
The exam is a written test. The questions are fully consistent with the arguments provided during the course which are all available on the DIR website. The written test comprises 4 open questions which require a concise answer. The written test is considered passed if the overall score is not less than 18. The score will be numerical and will progressively go to a maximum of 30 Laude (33 points), depending on the knowledge level of the student. During the written test it is not allowed to consult any microbiology textbooks.
Detailed Syllabus
CLINICAL PATHOLOGY
1. Reductionistic and holistic approach to laboratory medicine
2. Bayesian apprach and predictive powers (negative and positive)
3. Margin of error
4. Pre-analytic, analytic and post-analytic phases, localization of laboratory errors
5. Blood analysis
6. Haemostasis
7. Flow cytometry
8. Necrosis biomarkers
9. Inflammation biomarkers
10. Neoplastic biomarkers
11. Genetic diagnosis
12. Omic diagnosis

CLINICAL MICROBIOLOGY
Basic concepts of the microbiological diagnostics and techniques.
Diagnosis of the viral infections in the respiratory and gastrointestinal tract.
Diagnosis of the viral infections in the blood circulation system
Diagnosis of the infections in the urogenital tract and during pregnancy
Diagnosis of bacterial infections in the blood circulation system and the central nervous system.
Assessing and monitoring of antimicrobial resistance
Expected Learning Outcomes
CLINICAL PATHOLOGY
Critical interpretation of laboratory data.
Prescribing appropriateness of laboratory tests.
Knowledge of diagnostic profiles, diagnostic protocols and diagnostic
paths. Students must acquire autonomous judgement, ability to communicate using adequate terminology, and capacity of continuous updating

CLINICAL MICROBIOLOGY
The students must demonstrate: i) they have acquired the basic concepts of the diagnosis of infectious diseases, ii) an appropriate scientific language, and iii) they are able to use the supplied material for a critical and reasoned study.

Moduli

Course year 3
Code MS0966
Course CLINICAL PATHOLOGY
Lecturers Umberto DIANZANI
SSD MED/05
Campus ALESSANDRIA
Curriculum CORSO GENERICO
Credits 2
Course year 3
Code MS0967
Course CLINICAL MICROBIOLOGY
Lecturers Marisa GARIGLIO
SSD MED/07
Campus ALESSANDRIA
Curriculum CORSO GENERICO
Credits 1
Course year 3
Code MS0968
Course CLINICAL BIOCHEMISTRY AND CLINICAL MOLECULAR BIOLOGY
Lecturers Daniela CAPELLO
SSD BIO/12
Campus ALESSANDRIA
Curriculum CORSO GENERICO
Credits 2
Last update:09-09-2026 00:14:31