Ateneo - UPO

-Cytokines.
-Functions of T and NK cells.
-Immunological memory.
-Immunoelusion.
-Passive and active immunization.
-Immune deficiencies.
-Hypersensibility.
-Autoimmune diseases.
-Transplantation immunology
-Tumor immunology
-Immunomodulatory therapies

1) Dianzani-Pucillo, Immunologia e Immunopatologia. Edi Hermes
2) Coico, Immunologia, un precorso breve, Edi.Ermes,
3) Murphy, Immunobiologia di Janeway. Piccin

To acquire knowledges on the immune system function at the level of innate and adaptive immunity in order to understand also the mechanisms of immune evasion, vaccination, and the etiology and pathogenesis of allergic and autoimmune diseases. Students will acquire autonomous judgement, ability to communicate using adequate terminology, and capacity of continuous updating

Knowledge of basic cell biology and immunology

Frontal teaching with slides. The slides are available, including slides with vocal comment. Interactivity is promoted by discussion of scientific articles and optional attendance at the Immunology laboratory

Students with physical disabilities, Learning Disabilities or Special Education Needs can request
specific services and tools via the Staff Sviluppo e Coordinamento Carriere e Servizi alle Studentesse

e agli Studenti, consulting the University webpage: https://www.uniupo.it/en/services/services-
students-physical-or-learning-disabilities

Students with disabilities, learning disabilities or special education needs, once they have contacted
the University Staff, can refer to the tutor in charge of the course to define the examination
modalities, concerning academic aspects.

Oral examination assessing knowledge of the main principles and technical terminology of immunology

-Cytokines. Structure, function, receptors and signaling.
-Helper and cytotoxic activities aof T cells. Th1, Th2, Th17, natural and induced Treg, CTL, NK, NKT, Tγδ.
-Immune evasion. Mechanisms of immune evasion of infectious agents and tumors.
-Passive and active immunization. Vaccines.
-Acquired and congenital immune deficiencies.
-Type I, II, III, IV hypersensivity. Etiology, pathogenesis, examples.
-Autoimmune diseases. Etiology, pathogenesis, examples.
-Transplantation immunology. Hyperacute, acute, chronic rejection.
-Tumor immunology.
-Immunomodulatory therapies.

Molecular basis of immunology, also in relation to applications in the field of diagnostics and therapy. Cell type and molecules responsible for alterations of the immune response and
inflammation. Students must acquire autonomous judgement, ability to communicate using adequate terminology, and capacity of continuous updating