Ateneo - UPO

The course is divided into two parts: one dedicated to the fundamental concepts of radiobiology, and the other to radiation protection, covering both general principles and legislative regulations. The syllabus includes the interactions of ionizing radiation with cells and tissues; DNA damage and repair mechanisms; radiosensitivity; the linear-quadratic model; early and late tissue effects; deterministic and stochastic effects; ICRP documents; Euratom directives; and legislation regarding radiation protection.

RADIOBIOLOGIA E RADIOPROTEZIONE Carissimo Biagini Piccin 1999
ELEMENTI DI RADIOBIOLOGIA CLINICA E RADIOPROTEZIONE Roberto Orecchia, Giovanni Lucignani, Giampiero Tosi Archimedica 2001
PUBBLICAZIONI ICRP(39, 41, 44, 49, 52, 53, 57, 58, 59, 60, 61, 62, 73, 75)
DIRETTIVE CE (92/69, 97/43,59/13)
LEGISLAZIONE NAZIONALE (DL 26 maggio 2000, n. 187; DL 26 maggio 2000,n. 141; DL 31 luglio 2020, n. 101)

The module aims to provide fundamental knowledge and skills in radiobiology to facilitate an understanding of the use of ionizing radiation.
The biological basis of early and late side effects is outlined.
Incidents in diagnostic radiology, nuclear medicine, and radiotherapy are addressed.
Legislative aspects of radiation protection are also covered.

The student must be familiar with the fundamental concepts of physics and biology.

Lectures using PowerPoint presentations and video materials.
Open discussion on the main topics covered.
Periodic assessment of comprehension and information retention during lessons via mock multiple-choice quizzes.

No practical exercises are scheduled for this subject

Multiple-choice quiz forming part of the course examination.
The questions cover the topics addressed during the course. Students must demonstrate that they have grasped the fundamental concepts regarding the medical aspects of radiation protection and are familiar with the relevant regulatory and legislative principles.

Radiobiology. General overview of interactions between radiation and the human body.
Physical dose and biological parameters (DI, LET, RBE, equivalent dose).
Radiation protection. Review of physics and radiobiology concepts.
Main effects of ionizing radiation on tissues and organs. Natural background radiation and population dose. Worker classification and dose limits. Worker health surveillance. Accidents involving patients, staff, and the external environment in diagnostic radiology, radiotherapy, and nuclear medicine.
Patient radiation protection in diagnostic radiology, nuclear medicine, and radiotherapy: principles of justification, optimization, and dose limitation.
Legislative aspects: scope of application; health protection for workers, the general public, and patients

Acquisition of knowledge and skills regarding radiobiology.
Acquisition of knowledge and skills regarding radiation protection, with particular regard to measures to be adopted in the event of potential exposure to ionizing radiation.
Ability to apply this knowledge within the scope of one's professional practice.