Ateneo - UPO

Introduction to main aspect of organic chemistry and solution preparation

For "Chimica Organica":“Chimica di Base per le Scienze della Vita” Ed. Delfino, Roma. Volume II . Autore: M. Anastasia “Chimica Organica” Ed. Edi-Ermes Autore: B. Botta “Chimica Organica”Ed. Zanichelli Autori: K. P. C. Vollhardt – N. E. Shore “Fondamenti di Chimica Organica” Autore: D. KleinFor "Esercitazioni di chimica per discipline biomediche: Fondamenti di Stechiometria Giomini, Balestrieri, Giustino, edises

Provide students the essential elements of organic chemistry to critically approach the study of complex biomolecules, and the preparation of solution at fixed concentration

Main concepts developed in the course of General Chemistry (chemical bond, equilibria, kinetics and thermodynamics of chemical processes)

Exercises and problems will be solved and discussed during the course. All the material will be made available to students in the web

Students with physical disabilities, Learning Disabilities or Special Education Needs can request specific services and tools via the Staff Sviluppo e Coordinamento Carriere e Servizi alle Studentesse e agli Studenti, consulting the University webpage: https://www.uniupo.it/en/services/services-students-physical-or-learning-disabilities Students with disabilities, learning disabilities or special education needs, once they have contacted the University Staff, can refer to the tutor in charge of the course to define the examination modalities, concerning academic aspects.

The exam will be a set of multiple-choice questions aimed at developing the attitude to critical thinking of the candidate

Chimica Organica: Credit 1: Structure and properties of organic compounds 1. General introduction to the chemical bond 2. Covalent, ionic and polar covalent chemical bonds: properties and geometry-1 3. Lewis structural formulas and formal charges and resonance formulas 4. Aromaticity Credit 2: Functional groups, physical properties and nomenclature 5. Functional groups and their influence on physical and chemical properties (acidity and basicity) 6. Inter- and intra-molecular interactions and their effect on properties and reactivity 7. Nomenclature of organic compounds Credit 3: Isomerism, conformation and stereochemistry analysis 8. Isomerism: definition and classification 9. Conformational analysis of acyclic and cyclic compounds. Configurational analysis: alkenes 10. Chirality and configurational analysis: diastereomerism and enantiomerism Credit 4: Functional groups and their reactivity-1 11. Reactivity of alkanes, alkenes and alkynes: Electrophilic addition and catalytic hydrogenation 12. Alkyl halides and mono- and bimolecular nucleophilic substitution (SN) reactions 13. Mono- and bimolecular elimination reaction. Competition with SN 14. Alcohols and their reactivity Credit 5: Functional groups and their reactivity-2 15. Ethers, epoxides, thiols and thioethers 16. Amines 17. Carbonyl derivatives and nucleophilic addition reaction 18. Tautomerism and condensation reactions 19. Carboxylic acids and nucleophilic acyl substitution reactions 20. Derivatives of carboxylic acids Credit 6: Functional groups and their reactivity-3 / biomolecules 21. Benzene: aromaticity, nomenclature and properties 22. Reactivity of benzene and aromatic electrophilic substitution reactions 23. Phenols and aromatic amines. Aromatic nucleophilic substitution 24. Radical reactions 25. Amino acids and peptides 26. Sugars 27. Lipids

Esercitazioni di Chimica per Discipline Biomediche: introduction to solutions, suspensions, emulsions, and their differences. Introduction to the various chemical and physical units for the calculation of concentrations of solutions. exercises done in the classroom for learning evaluation. volumetric methods: theoretical and practical concepts of the use of titrations.

Recognize and critically evaluate the functions present in an organic molecule, knowing its properties and reactivity.