Ateneo - UPO

The course deals with the pathophysiological mechanisms related to senescence, blood perfusion, acid/base and hydro-saline homeostasis, hemostasis, iron and bilirubin alterations and neurodegeneration.

Pontieri. Patologia Generale e Fisiopatologia. Piccin.
Altucci, Berton, Stivala. Patologia generale vol.1 e 2 Funzioni differenziate di organi e sistemi. Idelson-Gnocchi

The course deals with the pathophysiological mechanisms related to senescence, blood perfusion, acid/base and hydro-saline homeostasis, hemostasis, iron and bilirubin alterations and neurodegeneration.

The students must have acquired adequate information of Biology, Anatomy, Physics, Chemistry, Biochemistry, Medical Genetics, Histology and Physiology.

Interactive class, discussion, reading scientific papers.

Students with physical disabilities, Learning Disabilities or Special Education Needs can request specific services and tools via the Staff Sviluppo e Coordinamento Carriere e Servizi alle Studentesse e agli Studenti, consulting the University webpage: https://www.uniupo.it/en/services/services-students-physical-or-learning-disabilities
Students with disabilities, learning disabilities or special education needs, once they have contacted the University Staff, can refer to the tutor in charge of the course to define the examination modalities, concerning academic aspects.

Oral exam. The student needs to have acquired information on the most important pathophysiological processes that cause disease.
Ability to apply the acquired information to the study of the mechanism of human disease is expected.

Senescence.
Hemostasis.
Physiopathology of blood perfusion: Ischemia, hyperemia, reperfusion syndrome. The shock
Physiopathology of acid/base regulation: acidosis and alkalosis
Physiopathology of iron. Regulation of body iron adsorption and distribution. Iron deficiency and overload.
Physiopathology of hydro-electrolytic homeostasis. Hydro-electrolytic alterations. The edema.
Pathophysiology of heme.
Pathophysiology of systemic and organ-specific amyloidoses
Gender mainstreaming: gender-specific aspects will be discussed for each disease.

The task of this course is to make the students able to understand the cause and the pathogenesis of disease.