Ateneo - UPO

Study of the tissues of the human body, set according to the morphological aspects, which in themselves lead to indications on the location and function of the same. How to interpret a histological preparation.
Study of the early periods of human development, of the
strategy / mechanism of how the different tissues in the embryo originate and how they combine to form organs. Stem cells from the early stages of development to the maintenance of tissues in adults (homeostasis).

Ross-Pawlina: Istologia – Testo e atlante con elementi di Biologia cellulare e molecolare – Casa Editrice Ambrosiana

Istologia di Monesi 7 edizione
Adamo, De Felici, Dolfi..
PICCIN

Wheater: Istologia e Anatomia microscopica, Edises

De Felici et al.: Embriologia Umana - Piccin
Barbieri-Carinci: Embriologia Umana: Casa Editrice Ambrosiana
Moore- Persaud: Lo sviluppo prenatale dell’uomo, Edises

At the end of the course the student must:
i) have acquired the basic knowledge of molecular and cellular components, of the structure, function and embryological origin of the different tissues of the human body;
ii) have acquired knowledge about tissue homeostasis;
iii) have acquired the basic knowledge of the first moments of embryonic development (first month)

The student should have the essential notions of Cell Biology, Cytology and biochemistry.
It would be better if the student has passed the biology exam

Lectures are held, using files in power point
Presentation and Video.

nothing

The exam consists of a compulsory written test (50 multiple choice questions
, of which only one is correct) and an oral interview, with recognition of the slide under the microscope.
Registration for the exam is mandatory.
For the written test, for the purpose of the vote, only the correct answers are considered. The tasks are performed on the DIR and are corrected quickly, so that the
students can know the outcome (number of correct questions) immediately.
Only those who passed the written test (correct answers about 80% of the
questions) can access the oral exam, which is also mandatory

- Coating epithelium. Cell polarization. Specializations
cytoplasmic and surface, related to protective functions,
mechanical, waterproofing and transport. Classification,
structure and physiology. Cell junctions, basement membrane.
-Exocrine glandular epithelium. Structure and classification. Specializations
of secretory functions. Mechanisms for regulating secretion.
- Endocrine glandular epithelia. Hormonal signals and tissue homeostasis.
Hypothalamic-pituitary axis. Functional histology of thyroid, adrenal and islets
pancreatic.
-The blood: plasma, serum, cells. Structure, average life, and function of
cells, leukocyte formula, hematocrit.
-Hemopoiesis. Multipotent and unipotent stem cells and precursors.
Regulation of hematopoiesis: bone marrow microenvironment and growth factors.
Hemocateresis.
-Lymphatic tissues: structure and organization of the lymphatic system.
Classification of lymphocytes, membrane markers. Lymphopoiesis e
maturation of lymphocytes. Functional specializations of B, T, NK and lymphocytes
plasma cells.
-Supporting tissues: components and function of the extracellular matrix.
Cells and their relationships with the matrix. Classification of fabrics
connectives. - Cartilage tissue and bone tissue. Mechanical functions e
of metabolic homeostasis. Ossification, growth, remodeling e
repair.
-Adipose tissue: white, brown and beige.
-Muscle tissue: skeletal, smooth, cardiac. Structure e
membrane, cytoskeletal and metabolic specializations.
Mechanism and regulation of muscle contraction.
- Blood vessels: structure. Capillaries and sinusoids. Vasculogenesis e
angiogenesis.
- Nerve tissue. Ultrastructural specializations of neurons. Transport
axonal. Electrical properties of the membrane. Synapse and neuromuscular junction.
Myelination. Gray matter and white matter. The ganglia, i
nerves. The daughter.
-Tissue homeostasis: Generalities on differentiation, maintenance and
tissue renewal: stem cells.
-Gametogenesis. Principles of anatomy and histology of the genital system
feminine and masculine. Germline cells and their maturation.
Ovarian cycle, uterine cycle and their hormonal control. Spermatogenesis e
its hormonal control.
- Embryonic development. Fertilization and fertilization. Zygote,
segmentation. Twins. Blastocyst and its implant. Bilaminar embryo
and trilaminar. The embryonic foldings. Prospective development of the three
embryonic leaflets. Embryonic appendages.

In order to achieve the knowledge and skills corresponding to the
minimum level of sufficiency, the student is asked to demonstrate:
(KNOWLEDGE) - know the molecular and cellular components, theirs
structuring in the different tissues of the human body; the contribution of these
in the formation of organs and systems / systems; morphological characteristics of the different tissues and their correlations with the
function; - know the basics of embryology: development of gametes, cycle of organs responsible for reproduction, development of the human embryo in
first month.
(SKILLS) - ability to recognize the different tissues in photographs of histological sections. (ABILITY
TRANSVERSAL) - be able to read, understand and comment scientific notions taken from textbooks or specialized literature -
know, or be able to trace, essential terminology.
-know how to evaluate the teaching provided.