Ateneo - UPO

Organization of the cell. The main animal tissues. Anatomy and organ function. Principles of developmental biology. Recognition tissues and organs. Cell differentiation: cases and principles.

Biologia Cellulare e Molecolare, Concetti ed esperimenti, Karp, EdiSES Elementi di Biologia cellulare, Wolfe et al., EdiSES Fondamenti di Biologia, Solomon et al., EdiSES Biologia molecolare della cellula, Alberts et al., Zanichelli Citologia e Istologia, Dalle Donne, EdiSES Istologia e Anatomia Microscopica, Wheater, CEA Istologia funzionale, Kerr, CEA Istologia ed Elementi di Anatomia Microscopica, Dalle Donne et al., EdiSES Elementi di Anatomia, Istologia e Fisiologia dell'uomo, Martini – Bartholomew, EdiSES Anatomia comparata dei Vertebrati, Liem et al., EdiSES Citologia e Istologia Bottone M. G. | Biggiogera M. UTET

The course aims to impart knowledge on the structure and organization of the cell in the context of the various tissues of the human and animal body. Subsequently, the course will explore the molecular mechanisms involved in embryonic development in model organisms and in cell differentiation

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lessons in class

Learning will be monitored through questions put to students during the lessons. Students with physical disabilities, Learning Disabilities or Special Education Needs can request specific services and tools via the Staff Sviluppo e Coordinamento Carriere e Servizi alle Studentesse e agli Studenti, consulting the University webpage: https://www.uniupo.it/en/services/services- students-physical-or-learning-disabilities Students with disabilities, learning disabilities or special education needs, once they have contacted the University Staff, can refer to the tutor in charge of the course to define the examination modalities, concerning academic aspects.

The exam consists only of a written test. The written test evaluates the student's ability to apply the knowledge acquired during the course and consists of three types of questions: A) multiple choice questions B) open-ended questions C) histological identification The level of difficulty of the questions corresponds to the program carried out and to the reference texts indicated on DIR. For each of the questions, for questions A, 1 point are assigned, for questions B up to 4 points, for questions C up to 2 points; the written test is considered passed if the overall assessment is not less than 18 points. During the written test it is not allowed to consult notes, books or other material. To achieve a passing grade, students must demonstrate a fundamental understanding of the core concepts and topics covered in the course. To achieve a high grade, the student must demonstrate an autonomy of judgment and a critical sense related to the topics covered, exposing their conclusions in a clear and logical way. The evaluation is expressed in thirtieths (minimum mark 18).

-Introduction to Biology -Macromolecule: Lipids, carbohydrates, proteins and nucleic acids -Panoramic view of the cellular compartments -Cellular membrane’s structure -Cell transport -Nucleus and nucleolus: structure and function -Cycle and cell mitosis -From DNA to proteins: duplication, transcription, translation -Endoplasmic reticulum and Golgi apparatus -Lysosome: Structure and function -Perossisome: Structure and function -Mitochondrion: Structure and function -Cytoskeleton. Microtubules. Microfilaments and intermediate filaments -Extracellular matrix components (ECM) and Cell-ECM interaction -Cell Signaling: mechanisms -Cell death: apoptosis and necrosis -Introduction to Microscopy and histological preparation. -Integumentary system: -Sense Organs -Bone tissue -Muscle tissue -Circulatory apparatus -Breathing apparatus. -Digestive apparatus -Excretory system. -Endocrine Apparatus -Nervous tissue and nervous system. -Introduction to development biology -Gametogenesis -Fertilization -Segmentation -Gastrulation -Neurulation

Knowledge and understanding: Acquisition of in-depth knowledge in the field of cell biology, tissue biology and developmental biology. Knowledge of the concepts and applications of cell biology, acquisition of appropriate scientific language. Knowledge and understanding skills applied: At the end of the course the student will be able to recognize biological macromolecules, recognize cellular and tissue structures, localize production processes of biological macromolecules, associate cell structures and functions, reconstruct transport and cellular communication processes, recognize the various stages of embryonic development and cell differentiation, classifying tissues according to their characteristics. Autonomy of judgment: Ability to critically analyse the elements related to cell biology, autonomy of judgment in the field of tissue and cell biology. Communication skills: Use an appropriate scientific vocabulary; describe scientific themes related to cellular and developmental biology, with a logical and rational approach. Learning ability: Ability to use the teaching material for a critical and reasoned study.