Ateneo - UPO

MELE
The aim of the course is to provide students with the knowledge of immunogenetics and histocompatibility. In particular, the role of the immunogenetic laboratory and of the CSE processing sector within the process of hematopoietic stem cell transplantation from both related and unrelated donors will be addressed. The topics of the EFI Accreditation for the immunogenetic laboratory and JACIE for the processing sector will also be addressed.

MAZZUCCO
The aim of the course is to provide students with the knowledge related to new biotechnologies and regenerative medicine. Regenerative medicine is applied in different fields and is translational on the different disciplines, therefore problems will be addressed in the various clinical areas: wound repair, bone regeneration and tissue in general

MELE
Slides; Lecture notes, articles

MAZZUCCO
Slides; Lecture notes, articles

MELE
The aim of the course is to provide students with the knowledge of immunogenetics and histocompatibility. In particular, the role of the immunogenetic laboratory and of the CSE processing sector within the process of hematopoietic stem cell transplantation from both related and unrelated donors will be addressed. The topics of the EFI Accreditation for the immunogenetic laboratory and JACIE for the processing sector will also be addressed.

MAZZUCCO
The aim of the course is to provide students with knowledge of the principles of regenerative medicine, with technical-scientific in-depth analysis of the biological materials, cells and growth factors used in different fields of application.

MELE
Knowledge of Immunogenetics and transplant biology

MAZZUCCO
biology and physiology of the cells, protein biochemistry

MELE
Frontal lessons. Expert seminars on specific topics. Visit to the laboratories of the Hospital.

MAZZUCCO
Frontal lessons. Seminars on specific laboratory areas and preparation techniques. Visit to Laboratory of Alessandria Hospital

MELE
Control of learning: discussion of the topics during the lessons. Learning will be monitored through questions put to students during the lessons.

MAZZUCCO
Control of learning: discussion of the topics during the lessons. Learning will be monitored through questions put to students during the lessons.
The teacher answers only to e-mail signed and coming from the domain: matricola@studenti.uniupo.it. Students with physical disabilities, Learning Disabilities or Special Education Needs can request specific services and tools via the Staff Sviluppo e Coordinamento Carriere e Servizi alle Studentesse e agli Studenti, consulting the University webpage: https://www.uniupo.it/en/services/services-students-physical-or-learning-disabilities Students with disabilities, learning disabilities or special education needs, once they have contacted the University Staff, can refer to the tutor in charge of the course to define the examination modalities, concerning academic aspects.

MELE - MAZZUCCO
The exam consists only of an oral test that will focus on all the topics covered during the course. It has the dual purpose of verifying the level of knowledge and understanding of the course contents and of evaluating the autonomy of judgment, the ability to learn and the ability to communicate.
To pass the test, the student must demonstrate that he understands at least the fundamental concepts and the most important results related to them; moreover, adequately stimulated, he must demonstrate that he is able to recognize the errors committed and therefore identify the correct ways; finally, he must be able to explain the topics in a comprehensible way.
To achieve a high grade, the student must demonstrate an autonomy of judgment and a critical sense related to the topics covered, exposing their conclusions in a clear and logical way.
The evaluation is expressed in thirtieths (minimum mark 18).

MAZZUCCO

MELE
Introduction to the course:
-The laboratory of Immunogenetic
-Working with workspaces and cleaning policies
-Wipe test
-DNA extraction
-HLA system
-HLA and diseases
-PCR-SSP
-PCR-SSO
-PCR-SBT
-Electrophoresis on agarose gel
-Transplantation of CSE
-IBMDR Registry
-Clean room and cryopreservation room
-Guidelines of cryopreservation room
-Sampling, freezing and storage of CSE
-CFU-GM colony
-Isolation of purified lymphoid and myeloid cells for chimerism testing
-Chimerism post CSE transplant
-EFI and JACIE Accreditation procedures
-Data Management

MAZZUCCO
Introduction to the course
- concepts of regenerative medicine
- main elements: cells, scaffolds, biomolecules
- main laboratory techniques
- quality controls

MELE - MAZZUCCO
Knowledge and understanding:
-Autonomy of judgment: ability to critically analyze the elements related to developmental biology, autonomy of judgment in the field.
-Communication skills: use an appropriate scientific vocabulary; describe scientific topics related with a logical and rational approach.
-Knowledge and understanding skills applied: at the end of the course, the student must associate experimental approach and instrumentation, recognize different phases of development.
-Learning ability: ability to use the teaching material for a critical and reasoned study.

MAZZUCCO