Ateneo - UPO

In this module of the course, the physical principles of Nuclear Magnetic Resonance, spectral analysis and structural determination of simple metal complexes and inorganic compounds will be developed. Particular attention will also be paid to the study of magnetometry and magnetochemistry in inorganic chemistry.

The course material will be made available on the DIR platform.
Recommended consultation of:
Online course on the site: http://www.cis.rit.edu/htbooks/nmr/inside.htm (J.P. Hornak);
H. Friebolin, "Basic One- and Two-Dimensional NMR Spectroscopy", VCH (available in the library)
- M. Brustolon, E. Giamello, Electron Paramagnetic Resonance - A Practitioner's Toolkit, Ed. John Wiley & Sons, Inc., Hoboken, New Jersey, 2009.

The course aims at providing a solid foundation of the principles of Nuclear Magnetic Resonance Spectroscopy and a preliminary knowledge of the basics of the EPR technique. Particular attention will be paid to the development of the ability to interpret one-dimensional and multinuclear spectra of simple inorganic compounds in the light of theoretical concepts.
The course as a whole also aims to develop the ability to learn independently and the critical sense that allows the student to draw conclusions on issues related to the topics covered. Finally, the student will develop their communication skills by acquiring and using a chemical language appropriate to the topics of the course.

Principles of the General and Inorganic Chemistry and Physical Chemistry

Lectures integrated with some classroom exercises and related discussion and analysis of one-dimensional NMR spectra.

The concepts covered by the course will be discussed collegially in the classroom and applied directly during classroom exercises for the interpretation of spectra of inorganic compounds, obtained with the spectroscopic and resonance techniques subject of the course.
Students with physical disabilities, Learning Disabilities or Special
Education Needs can request specific services and tools via the Staff
Sviluppo e Coordinamento Carriere e Servizi alle Studentesse e agli
Studenti, consulting the University webpage:
https://www.uniupo.it/en/services/services-students-physical-or-learning-disabilities

Students with disabilities, learning disabilities or special education
needs, once they have contacted the University Staff, can refer to the
tutor in charge of the course to define the examination modalities,
concerning academic aspects.

Written exam of 2h consisting of 5 questions (which include both theoretical open questions and small exercises in the interpretation of spectra of inorganic compounds). The highest grade is achieved with solid knowledge and the ability to apply knowledge on all topics covered. The results of the exam highlight the degree of understanding of theoretical concepts and the degree of acquisition of an adequate technical-scientific language through the answers to the open questions. The autonomy of judgment is also assessed through the request to express judgments and make comparative choices, and the ability to learn independently.

Spectroscopic methods based on Magnetic Resonance for the study of the molecular structure and dynamic processes will be studied. Basic principles of the technique; nuclei in a magnetic field; resonance; population of nuclear spin levels; continuous wave experiment. Pulse NMR method: generalities, pulse angle, rotating coordinate system, Bloch equations, relaxation, Fourier transform. NMR parameters: chemical shift (diamagnetic, paramagnetic and local contributions) and coupling constants (geminal, vicinal, long-range, homo- and heteronuclear). Chemical and magnetic equivalence of nuclei. Order of an NMR spectrum. Examples of NMR spectra of multinuclear inorganic compounds. Brief outline of the basic principles of magnetometry/magnetochemistry and its application in the characterization of paramagnetic metal-coordination compounds.

Knowledge and understanding: knowledge of the theoretical bases of NMR spectroscopy, of the most used NMR techniques and their applications; know the principles for assigning and predicting 1H spectra of simple inorganic molecules. Knowledge of the fundamentals of EPR spectroscopy.
Ability to apply knowledge and understanding: ability to apply theoretical knowledge to the interpretation of spectra obtained from spectroscopic
resonance techniques.
Autonomy of judgment: Ability to critically analyze the notions learned.
Communication skills: ability to use appropriate scientific language in answering questions, in analyzing spectral data; acquisition of an appropriate scientific language to communicate in a precise, concise and clear way.
Learning skills: ability to use the teaching material for a critical and reasoned study that allows the subsequent autonomous acquisition of further knowledge in the field of NMR spectroscopy and other spectroscopic and magnetic techniques covered by the course.