Ateneo - UPO

The course provides knowledge of the structure, organization, and transmission of hereditary material in prokaryotic and eukaryotic organisms. The course provides basic elements of formal genetics.

RUSSEL P.J. Genetica “un approccio molecolare”, Ed. Pearson SNUSTAD P.D., SIMMONS M.J.- Principi di genetica, Ed. EdiSES. GRIFFITHS A.J.F., GELBART W., LEWONTIN R.C., SUZUKI D.T., MILLER J.H., WESSLER S.R. Genetica - Principi di analisi formale, Ed. Zanichelli.

The course aims to teach students the basics of the organization, expression and transmission of the genetic material, and the basics of the principles of heredity, of the Mendelian traits and its extensions. It will provide students with the basics of the quantitative genetics.

Basic knowledge of biology.

Class lectures with PowerPoint projections and use of blackboard for easy exercises explanation

Students with physical disabilities, Learning Disabilities or Special Education Needs can request specific services and tools via the Staff Sviluppo e Coordinamento Carriere e Servizi alle Studentesse e agli Studenti, consulting the University webpage: https://www.uniupo.it/en/services/services-students-physical-or- learningdisabilities Students with disabilities, learning disabilities or special education needs, once they have contacted the University Staff, can refer to the tutor in charge of the course to define the examination modalities, concerning academic aspects.

The course does not include any verification of learning, as it is supplementary teaching

The genetic material: chemical composition and structure. Replication, transcription and translation of genetic material. DNA organization in prokaryotic and eukaryotic chromosomes. Cell division: mitosis and meiosis. Mendel's laws and their applications. Human mendelian genetics: interpretation of pedigrees. Extension of mendelian analysis: multiple alleles and genetic interaction (epistasis, penetrance and expressivity). Chromosome theory of heredity. Sex chromosomes and sex determination. microorganisms: bacteria, bacteriophages and yeast. Exchange of genetic material: conjugation, transformation and transduction. Principles of quantitative genetics.

To know the structure, replication and transmission of the genetic material. To understand the bases of the Mendelian inheritance and of the interaction among genes. To know the principles of in planta genetic transformation. To understand the basics of quantitative traits and the difference with qualitative traits