Ateneo - UPO

Observation and description at the optical microscopy of the histological specimens relative to the course of Histology and Embryology

1) Ross, Pawlina - Istologia - Casa editrice ambrosiana
2) Cristiana Angelucci , Antonia Follenzi , Monica Mattioli Belmonte, Istologia umana, Idelson Gnocchi

Knowledge of the morphological characteristics of the human, and rodent tissues from histological specimens. Ability of identifying human tissues and cells. Moreover the students will acquire judgemnt indipendence, knowledge on histology and comunications skills

Basic knowledges of cytology and biology

Introductory lectures to explain how to observe histological sections under the microscope followed by direct observation of histological sections under the optical microscope

Students with physical disabilities, Learning Disabilities or Special Education Needs can request specific services and tools via the Staff Sviluppo e Coordinamento Carriere e Servizi alle Studentesse e agli Studenti, consulting the University webpage: https://www.uniupo.it/en/services/services-students-physical-or-learning-disabilities Students with disabilities, learning disabilities or special education needs, once they have contacted the University Staff, can refer to the tutor in charge of the course to define the examination modalities, concerning academic aspects.

An initial written exam with multiple-choice questions to be completed on a computer (in common with the Human Histology and Embryology course). Once a student passes the written exam, there will be given an oral exam involving observation of a histological preparation under a light microscope. Students must be able to recognize and describe the histological preparation.

Knowledge of the main histological stains and the use of the various microscopes available in histology. Theoretical knowledge acquired simultaneously in the Human Histology and Embryology course: - Epithelial tissues. Cellular polarization. Cytoplasmic and surface specializations, related to protective, mechanical, barrier and transport functions. - Classification, structure. Cytoskeleton, cell junctions, basement membrane. - Tegumentary system - Exocrine glandular epithelia. Structure and classification. Specializations of secretory functions. Histology of salivary glands, Brunner’s glands, exocrine pancreas - Endocrine glandular epithelia. Hormonal signals and tissue homeostasis. Hypothalamo-hypophyseal axis. Histology of thyroid, adrenal gland, pancreatic islets, Leydig’s cells - Connective tissues: components and functions of the extracellular matrix. Cells and their relationships with the matrix. Classification of connective tissues. - Blood: plasma, serum, cells. Cell structure, life span, and function, leukocyte formula. - Hemopoiesis. Multipotent stem cells and precursors. Hemocateresis. Histology of bone marrow - Lymphatic tissues: structure and organization of the lymphatic system. Classification of lymphocytes, membrane markers. Lymphopoiesis and lymphocyte maturation. Histology of thymus, spleen and lymph nodes - Cartilage and bone tissue. Mechanical functions and metabolic homeostasis. Ossification, growth, remodeling. - White and brown adipose tissue - Muscular tissue: skeletal, smooth, cardiac. Membrane, cytoskeletal and metabolic structure and specializations. Mechanism and regulation of muscle contraction. - Blood vessels: structure. Capillaries and sinusoids. - Nervous tissue. Ultrastructural specializations of neurons. Axonal transport. Electrical properties of the membrane. Synapses and neuro-muscular junction. Myelination. Gray matter and white matter. Description of glial cells

Ability to use the optical microscope; - ability to recognize and describe histological sections of normal tissues constituting the human organism; - ability to understand the basic tools for cellular and tissue investigation and the methods for their study